ABSTRACT
Liver involvement by multiple arterio-venous shunts in hereditary hemorrhagic telangiectasia can lead to severe heart failure. Total hepatectomy with liver transplantation has emerged as a therapeutic option for severe cases where other therapies have failed. We report a 51-year-old male who underwent a liver transplant for this condition, with full cardiac recovery within the first year after receiving the allograft. Nine years after transplantation, he remains with normal functional capacity and normal liver function tests.
Subject(s)
Humans , Male , Middle Aged , Telangiectasia, Hereditary Hemorrhagic/complications , Liver Transplantation/methods , Heart Failure/surgery , Anastomosis, Surgical , Treatment Outcome , Heart Failure/etiology , Liver/pathologyABSTRACT
Primary hyperaldosteronism is the most prevalent cause of secondary hypertension. Approximately 10 percentof hypertensive patients may be carriers of this condition. Idiopathic bilateral adrenal hyperplasia (HSBI) and aldosterone producing adenoma (APA) are the most common causes of hyperaldosteronism. To diagnose these conditions, adrenal venous catheterization (CVS) is the test of choice to evaluate functional imagingfindings. The aim of this communication is to demonstrate the usefulness of the CVS in the etiological diagnosis of this condition. We report two patients with primary hyperaldosteronism who were subjected to CVS. A male in whom and abdominal CAT scan showed bilateral adrenal growth, that was severest atthe left side. CVS concluded hyper secretion of aldosterone on the right side, but without suppression of the contralateral gland, corresponding to a bilateral adrenal hyperplasia. A 43 years old male in whom an abdominal CAT scan showed a right adrenal tumor measuring 11 x 5 mm. CVS showed a right lateralization of aldosterone secretion, with suppression of the contralateral gland. The conclusion was the presence of an aldosteronoma, which was excised by laparoscopy with excellent clinical outcome.
Subject(s)
Humans , Male , Middle Aged , Adenoma/diagnosis , Hyperaldosteronism/etiology , Hyperplasia/diagnosis , Adrenal Gland Neoplasms/diagnosis , Aldosterone , Catheterization , Adrenal Glands/pathology , Tomography, X-Ray ComputedABSTRACT
Chemoembolization is a therapeutic alternative for those patients with hepatocarcinoma that cannot be excised surgically or that are waiting a liver allograft. We report two patients with hepatocarcinoma who were subjected to chemoembolization. A 65 years old male with a chronic liver disease and right lobe hepatocarcinoma, waiting for a liver transplantation, was subjected to two sessions, of chemoembolization four weeks apart. A magnetic resonance showed a 80 percent reduction of tumor volume one month later. A 72 years old diabetic male with an alcoholic liver disease with two hepatocarcinoma in the right lobe was subjected to two sessions of chemoembolization, separated by four weeks. A magnetic resonance one month later showed the absence of blood flow in both lesions, suggesting complete necrosis.
Subject(s)
Aged , Humans , Male , Carcinoma, Hepatocellular/therapy , Chemoembolization, Therapeutic/methods , Liver Neoplasms/therapy , Angioplasty , Carcinoma, Hepatocellular/pathology , Carcinoma, Hepatocellular , Chronic Disease , Liver Cirrhosis/pathology , Liver Cirrhosis/therapy , Liver Neoplasms/pathology , Liver Neoplasms , Liver Transplantation/pathology , Neoplasm Staging/methods , Preoperative Care , Treatment OutcomeABSTRACT
Objetivo: evaluar la utilidad de las endoprótesis metálicas autoexpandibles en el tratamiento de la obstrucción colorrectal secundaria a una neoplasia maligna. Material y métodos: se instalaron un total de doce endoprótesis en doce pacientes bajo fluorscopica, en dos casos asistido por endoscopía. Los pacientes presentaban signos clínicos y radiológicos de una obstrucción intestinal a nivel colorrectal. Las indicaciones de instalación fueron: tratamiento paliativo en 10 pacientes con evidencias de enfermedad tumoral a distancia (9) o pelvis congelada (1) y en 2 pacientes como método de descompresión prequirúrgica. Se utilizaron prótesis metálicas autoexpandibles (Wallstent 20 x 55 mm). Resultados: la colocación de la endoprótesis fue exitosa en 12 pacientes, que se recuperaron de su obstrucción colónica dentro de las 24 horas siguientes. Conclusión: la instalación de endoprótesis autoexpandibles en pacientes con obstrucción intestinal a nivel colorrectal es un método mínimamente invasivo, efectivo como tratamiento paliativo en aquellos pacientes de alto riesgo para una intervención quirúrgica. Por otra parte, éste procedimiento también permite la preparación preoperatoria del colon y así proceder en una sola etapa quirúrgica